The typical college professor is bound to run into his or her share of difficult students during the course of an academic career. Some students create nuisances by engaging in annoying behavior, such as interfering with classroom proceedings, making irrelevant comments, and causing noisy interruptions. They may turn assignments in late, disregard the course expectations, and insist on special treatment for themselves. Other students, however, may pose a very real threat to the safety of the professor and fellow students. Relatively few college professors are trained in how to recognize and respond effectively to these challenging or threatening behaviors. Sometimes, faculty will have difficulty distinguishing between a student who is a mere nuisance and a student who poses a very real threat to the community. It is comforting to know that many of the most difficult and disruptive encounters with students tend to fall into predictable, known categories. This white paper will help you to set enforceable standards, expectations, and boundaries flexibly with students, depending on the exhibited personality style. After reading this white paper, you will know how to better manage passive-aggressive behaviors such as sleeping in class, lateness, and procrastination. You will learn essential principles regarding the value of collaborating with on-campus resources to resolve disruptive crises. This white paper also provides guidance to help professors know whether and when they need to report certain disruptive incidents. Perhaps most important, this report provides the guidance necessary to help instructors and administrators recognize “red flags” that portend physical risk when dealing with potentially dangerous students.